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Paul Lietman spacer
Paul Lietman, MD, PhD
Professor, Medicine, and Pediatrics, and Pharmacology and Molecular Sciences

Johns Hopkins University
School of Medicine, Department of Medicine
1830 E. Monument Street, Suite 7100
Baltimore, MD 21287
Phone: 410-955-3224

Email: plietman@jhmi.edu
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Research Interests:
International clinical research, development of complementary and alternative medicines, ethics of human experimentation, and clinical pharmacology of antiviral drugs


Selected Publications:
Moore MR, Hamzeh F, Lee FE-H and Lietman PS (1994) Activity of (S)-1-(3-Hydroxy-2-Phosphonylmethoxypropyl) Cytosine against human cytomegalovirus when administered as single-bolus dose and continuous infusion and in vitro cell culture perfusion system. Antimicrob Agents Chemother. 38:2404-8.

Cantú TG, Yamanaka-Yuen NA and Lietman PS (1994) Serum vancomycin concentrations: Reappraisal of their clinical value. Clin Infect Dis. 18:533-43.

Hendrix CW, Petty BG, Woods A, Kuwahara SW, Witter FR, Soo W, Griffin DE and Lietman PS (1995) Modulation of alpha-interferon's antiviral and clinical effects by aspirin, acetaminophen, and prednisone in healthy volunteers. Antiviral Res 28:121-31

Wachsman M, Petty BG, Cundy KC, Jaffe HS, Fisher PE, Pastelak A and Lietman PS (1996) Pharmacokinetics, safety and bioavailability of HPMPC (cidofovir) in human immunodeficiency virus-infected subjects. Antiviral Res 29:153-61.

Barditch-Crovo P, Deeks SG, Collier A, Safrin S, Coakley DF, Miller M, Kearney BP, Coleman RL, Lamy PD, Kahn JO, McGowan I, and Lietman PS (2001) Phase I/II trial of the pharmacokinetics, safety, and antiretroviral activity of tenofovir disoproxil fumarate in human immunodeficiency virus-infected adults. Antimicrob Agents Chemother. Oct. 45(10):2733-9.

Lewis, LD, Amin S, Civin CI, Lietman PS (2004). Ex vivo zidovudine (AZT) treatment of CD34 / bone marrow progenitors causes decreased steady state mitochondrial DNA (mtDNA) and increased lactate production. Hum Exp Toxicol 23:173-85.



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