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Research
Interests:
International clinical research, development
of complementary and alternative medicines, ethics of
human experimentation, and clinical pharmacology of
antiviral drugs
Selected
Publications:
Moore MR, Hamzeh F, Lee FE-H and Lietman PS (1994) Activity of (S)-1-(3-Hydroxy-2-Phosphonylmethoxypropyl) Cytosine against human cytomegalovirus when administered as single-bolus dose and continuous infusion and in vitro cell culture perfusion system. Antimicrob Agents Chemother. 38:2404-8.
Cantú TG, Yamanaka-Yuen NA and Lietman PS (1994) Serum vancomycin concentrations: Reappraisal of their clinical value. Clin Infect Dis. 18:533-43.
Hendrix CW, Petty BG, Woods A, Kuwahara SW, Witter FR, Soo W, Griffin DE and Lietman PS (1995) Modulation of alpha-interferon's antiviral and clinical effects by aspirin, acetaminophen, and prednisone in healthy volunteers. Antiviral Res 28:121-31
Wachsman M, Petty BG, Cundy KC, Jaffe HS, Fisher PE, Pastelak A and Lietman PS (1996) Pharmacokinetics, safety and bioavailability of HPMPC (cidofovir) in human immunodeficiency virus-infected subjects. Antiviral Res 29:153-61.
Barditch-Crovo P, Deeks SG, Collier A, Safrin S, Coakley DF, Miller M, Kearney BP, Coleman RL, Lamy PD, Kahn JO, McGowan I, and Lietman PS (2001) Phase I/II trial of the pharmacokinetics, safety, and antiretroviral activity of tenofovir disoproxil fumarate in human immunodeficiency virus-infected adults. Antimicrob Agents Chemother. Oct. 45(10):2733-9.
Lewis, LD, Amin S, Civin CI, Lietman PS (2004). Ex vivo zidovudine (AZT) treatment of CD34 / bone marrow progenitors causes decreased steady state mitochondrial DNA (mtDNA) and increased lactate production. Hum Exp Toxicol 23:173-85.
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