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Research
Interests:
Chemoprevention of HIV infection; topical
HIV microbicides; clinical pharmacology of antiviral
drugs; drug interactions
Selected Publications:
Hendrix CW, Jackson KA, Whitmore E, Guidos A, Kretzer R, Liss CR, Patel-Shah L, McLane J, Trapnell CB (2004) The Effect of Isotretinoin on the Pharmacokinetics and Pharmacodynamics of Ethinyl Estradiol and Norethindrone. Clin Pharm Ther 75:464-475.
Hendrix CW, Wakeford J, Wire MB, Bigelow G, Cornell E, Christopher J, Fuchs E, Snidow J (2004) Pharmacokinetic and pharmacodynamic evaluation of methadone enantiomers following co-administration with amprenavir in opioid-dependent subjects. Pharmacotherapy 24(9):1110-21.
Hendrix CW, Collier AC, Lederman MM, Schols D, Pollard RB, Brown S, Jackson JB, Coombs RW, Glesby MJ, Flexner CW, Bridger GJ, Badel K, MacFarland RT, Henson GW, Calandra G, AMD3100 HIV Study Group (2004) Safety, Pharmacokinetics, and Antiviral activity of AMD3100, a selective CXCR4 Receptor Inhibitor, in HIV-1 Infection. JAIDS 37:1253-62.
Ndovi TT, Choi L, Caffo B, Parsons T, Baker S, Zhao M, Rohde C, Hendrix CW (2006) Quantitative seminal vesicle and prostate drug concentrations using a non-invasive method. Clin Pharmacol Ther, 80:146-58.
Ndovi TT, Parsons T, Choi L, Caffo B, Rohde C, Hendrix CW. (2006) A new method to quantitatively estimate seminal vesicle and prostate gland contributions to ejaculate. Br J Clin Pharmacol Oct 31; [Epub ahead of print].
Mayer KH, Maslankowski L, Gai F, El-Sadr W, Justman J, Kwiecien A, Masse B, Eshleman S, Hendrix CW, Morrow K, Absalon J, Rooney J, Soto-Torres L. Tenofovir vaginal gel: Safety and tolerability in low-risk HIV-uninfected women and HIV-infected women (HPTN 050). AIDS 2006; 20(4): 543-551.
Fuchs EJ, Lee LA, Torbenson MS, Parsons TL, Bakshi RP, Guidos AM, Wahl RL, Hendrix CW. Hyperosmolar Sexual Lubricant Causes Epithelial Damage in the Distal Colon: Potential Implication for HIV Transmission. J Infect Dis (In Press)
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